The Use of Urea Creams for the Foot

Urea is an natural and organic substance that is probably most familiar because of its purpose within a fertilizer utilized in farming. Urea takes on an important part in your bodies metabolic process and is a vital method by which the body excretes excessive nitrogen. Urea is manufactured in your liver from an ammonia compound via the breakdown of amino acids as the major end product of proteins metabolism. Urea is made up of a pair of amine chemical groups that are joined with each other by a carbonyl chemical group. Back in 1928 Friedrich Wöhler showed for the first time that the organic substance might be made out of inorganic substances as he had been able to make urea from inorganic precursors in the research laboratory. The manufactured form of urea is commonly used as a topical cream or external medicine used to care for a number of skin conditions. It’s become very important for this that urea currently is listed by the World Health Organisation with their List of Essential Medications that it suggests that most nations be able to access. In skin which is dried out, it has been demonstrated that there’s a considerable decrease of urea in the skin, so hence the need to apply the urea products. These kinds of skin complaints include simple skin conditions such as dried-out skin or the more severe skin problems for example psoriasis, eczema along with ichthyosis. These creams are frequently used by podiatric doctors following the removal of cracked skin surrounding the heels.

These urea creams have got varying affects on various skin disorders based upon their content level in the medication. With concentrations close to 40% the urea may reduce the cellular matrix of the nail plate and so could be used to deal with nail dystrophy conditions by dissolving an area of the nail. This could be useful in problems such as fungal infections of the toenails. At concentrations under that, yet still above 20% the urea cream is known as a keratolytic which implies you can get a dysfunction of proteins within the epidermis, and so the dried-out skin will flake off, especially with the cracked dry skin around the heel of the foot. At concentrations of lower than about 20% the urea product works as a humectant which suggests it may help the skin keep moisture and lower water loss and make the skin soft and also supple. Urea comes with a extra benefit because it also features anti itching affects which means that it will help with the dryer skin problems that are additionally itchy. There are not really any side effects by using these urea products on the epidermis aside from an infrequent local irritability that almost usually clears up once you cease making use of the urea product. In contrast to a lot of other medications, there are no known interactions in between urea and other medicines that could be utilized. Urea really should not be used when there is a recognized hypersensitivity to urea or any of the different ingredients that are used when making the product. You will find literally hundred’s of various brand names of urea creams such as Walker’s Urea Foot Cream from Australia and the Glycolix Glyco-Urea KP Therapy from the US. Always steer clear of exposure to the eyes with the urea product and rinse the hands soon after using it.

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